Ipamorelin

Ipamorelin research material, available in 5 mg, 10 mg vials. For in-vitro research only.

• The peptide is Aib-His-D-2-Nal-D-Phe-Lys-NH2, identified within a chemistry series that lacks the central Ala-Trp dipeptide of growth hormone releasing peptide 1. [1]
• In primary rat pituitary cells it released growth hormone with an EC50 of 1.3 nmol/l and an efficacy of 85 percent of the GHRP-6 maximum, and antagonist profiling placed the response at a GHRP-like receptor rather than the growth hormone releasing hormone receptor. [1]
• In pancreatic tissue fragments from normal and streptozotocin-diabetic rats it evoked insulin release across 10 to the minus 12 through 10 to the minus 6 molar, and a calcium channel blocker or adrenergic antagonists reduced that release. [2]
• The pentapeptide backbone has been reused for fluorine-18 labeled and boron-rich ghrelin receptor ligands, with binding and activation measured for those derivatives rather than for the parent peptide. [3] [4]

Compound

Ipamorelin

Purity

99.40% (HPLC)

Identity

Confirmed by MS

Appearance

White lyophilate

Presentation

5 mg · 10 mg

Catalog / lot

RV-0037 / RV-24-0037-1

For research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or supplement.

Review the laboratory, lot identifier, and reported results in this document. Keep the lot identifier with your research records.